Having previously been based in Mayfair in the West End, the company has now moved its staff over into a substantial area of office space at the 2 Kingdom Street Tower in Paddington Central.
See our guide to Opening an Office in Mayfair here
Mr Johnson was keen to cite AstraZeneca’s commitment to London as evidence that international businesses are keen to continue operating from prominent sites across the city.
Three floors of office space will soon be occupied by over 300 of the organisation’s staff, with many of them involved with various marketing initiatives and sales operations throughout Europe and the world.
AstraZeneca’s move from the West End to Paddington follows a recent announcement from the investment bank JPMorgan that it intends to establish a new European operating base in Canary Wharf, a few miles south-east of ‘the City’ and a major financial services hub in its own right.
See our guide to Opening an Office in Canary Wharf here
In reference to Paddington, Mr Johnson remarked: “This once derelict part of London has transformed itself into a thriving new business district providing quick access to the capital’s transport network, its airports and its centres of world-class research.
“With Crossrail passing through Paddington in the near future, many more businesses will be heading west to reap the huge business benefits AstraZeneca has discovered in this fantastic corner of the capital.”
In addition to world-class office space to rent on a leasehold basis in Paddington, a wide range of flexible office and workspace solutions is available.
See profiles of providers of flexible office spaces in Paddington here
The solutions include furnished, ready-to-use private serviced offices, managed office suites, and co-working desk spaces.
All are available on short-term agreements and on all-inclusive rental arrangements.
The cost of renting office space in London is expected to increase considerably over the next few years, with demand set to outstrip supply by some distance. The city was, however, rated by Cushman & Wakefield as being the best place in the world in which to do business.
Editor’s notes: In February 2022, it was announced that AstraZeneca had rented a further 22,000 square feet of office space at Pancras Square in King’s Cross. This was in addition to the 15,000 square feet of space it had occupied since 2019 and, in turn, made the Knowledge Quarter at Kings Cross AstraZeneca’s new London headquarters.
Check out our Guide to Opening an Office in Kings Cross here.
As of June 2026, AstraZeneca’s London office remained listed as 2 Pancras Square, London N1C 4AG.
Also in June, it was reported that the AstraZeneca CEO said AI was reshaping drug development and improving the odds of success.
In April, it had been reported that AI firm Anthropic had agreed to lease 158,000 square feet of office space at One Triton Square in the heart of Regent’s Place on London’s ‘Smart Mile’ within the capital’s Knowledge Quarter.
In the same month, OpenAI had signed a lease for 88,500 square feet at nearby Regent Quarter.
These would join the Centre for the Governance of AI and ON24 in the Knowledge Quarter, as well as Google, which was due to officially move into its new 1 million-square-foot headquarters, named Platform 37, in the summer.